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Herb

Rosehip Extract

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Rosehip Extract. Standardized GOPO® rosehip powder for osteoarthritis.

How it works. Galactolipid GOPO inhibits chemotaxis of neutrophils into joints.

What the research supports. 1 graded claims. Strongest: Reduces OA pain and analgesic use (strong).

How much to take. Typical dose: 5 g/day standardized to GOPO.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with A high-quality multivitamin, Omega-3 (EPA/DHA).

Common forms. Available as Standardized extract capsule, Liquid tincture (alcohol or glycerin), Powdered whole herb, Traditional decoction or tea.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Rosehip Extract. Anecdotes are not medical advice.

Rosehip Extract. Standardized GOPO® rosehip powder for osteoarthritis.

Key compound: tilirosideC30H26O13 · 594.5 g/mol

What it is

Standardized GOPO® rosehip powder for osteoarthritis.

Also called

Rosa canina

Food sources

Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice

How it works

Galactolipid GOPO inhibits chemotaxis of neutrophils into joints.

Pathways

  • Galactolipid GOPO inhibits chemotaxis of neutrophils into joints

Effects

  • ↓OA pain and analgesic use decreases

What the research supports

Reduces OA pain and analgesic usestrong

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
5 g/day standardized to GOPO
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodWith meals
Best formMost evidence is based on the standardized extract capsule form.
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Side effects & interactions

Common side effects

  • GI upset

Medication interactions

Prescription medications (general)minor

Always disclose Rosehip Extract use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
  • Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.

Common forms

  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Key studies

8 studies cited in total.

Rosehip meta-analysis in OA ↗
Meta-analysis · Osteoarthritis Cartilage · 2008

Significant pain reduction vs placebo with NNT of 6.

PubMed: Rosehip Extract — Reduces OA pain and analgesic use ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Rosehip Extract and "Reduces OA pain and analgesic use". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Rosehip Extract — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Rosehip Extract and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

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