Overview
Active form of resveratrol.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Activates SIRT1; mimics caloric restriction.
- · Activates SIRT1
- · mimics caloric restriction
Effects on the body
Organ system effects
Trans-Resveratrol acts on hallmarks of aging including oxidative stress, mitochondrial dysfunction, and senescence signaling.
Trans-Resveratrol supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
Evidence-based benefits
Improves insulin sensitivity
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Supplement interactions
- NAD+ precursor (NMN or NR)Complementary mitochondrial and sirtuin support.
- Omega-3Lowers inflammation and supports membrane integrity.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Trans-Resveratrol — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Trans-Resveratrol third party tested NSF
CapsulesPre-measured Trans-Resveratrol capsules — easiest for travel and consistent daily dosing without scoops or scales.Trans-Resveratrol capsules
PowderBulk unflavored Trans-Resveratrol powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Trans-Resveratrol powder unflavored
Best sellersMost-purchased Trans-Resveratrol products on Amazon — a quick way to see what's reviewed widely before you commit.Trans-Resveratrol best sellerScientific evidence8Show studiesHide studies
Trans-resveratrol meta-analysis
Liu K, et al.
11 RCTs
Improved glucose control in T2DM.
PubMed: Trans-Resveratrol — Improves insulin sensitivity
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PubMed: Trans-Resveratrol — randomized controlled trial
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PubMed: Trans-Resveratrol — meta-analysis
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PubMed: Trans-Resveratrol — pharmacokinetics
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PubMed: Trans-Resveratrol — safety adverse events
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PubMed: Trans-Resveratrol — dose response
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Google Scholar: Trans-Resveratrol — clinical evidence
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Cross-database citation index for Trans-Resveratrol as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.