Overview
Mucosal protective for gastritis.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Increases prostaglandins and mucus secretion.
- · Increases prostaglandins
- · mucus secretion
Effects on the body
Organ system effects
Rebamipide influences gut motility, mucosal integrity, or microbial balance in the GI tract.
Evidence-based benefits
Prevents NSAID gastropathy
Moderate evidencePotential side effects
- · Constipation
Drug interactions
Supplement interactions
- Multi-strain probioticSupports microbiome diversity and barrier integrity.
- L-glutamineSubstrate for enterocyte energy and tight-junction maintenance.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Rebamipide for NSAID gastropathy
Yamashita K, et al.
30 patients
Prevented NSAID-induced injury.
PubMed: Rebamipide — Prevents NSAID gastropathy
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PubMed: Rebamipide — randomized controlled trial
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PubMed: Rebamipide — meta-analysis
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PubMed: Rebamipide — pharmacokinetics
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PubMed: Rebamipide — safety adverse events
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PubMed: Rebamipide — dose response
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Google Scholar: Rebamipide — clinical evidence
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