Supplement Scholar
Compound

Quercetin + Dasatinib (D+Q)

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Quercetin + Dasatinib (D+Q). Reference senolytic combination cycled to clear senescent cells.

How it works. Inhibits anti-apoptotic Bcl-XL and SRC family kinases in senescent cells.

What the research supports. 1 graded claims. Strongest: Improves physical function in IPF (open-label) (limited).

How much to take. Typical dose: Research protocols only.

Side effects and interactions. 1 medication interaction listed. Serious: Use only with medical oversight.

Stacking. Pairs well with NAD+ precursor (NMN or NR), Omega-3.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Quercetin + Dasatinib (D+Q). Anecdotes are not medical advice.

Quercetin + Dasatinib (D+Q). Reference senolytic combination cycled to clear senescent cells.

Molecular structureC15H10O7 · 302.23 g/mol

What it is

Reference senolytic combination cycled to clear senescent cells.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

Healthy Aging

How it works

Inhibits anti-apoptotic Bcl-XL and SRC family kinases in senescent cells.

Pathways

  • Inhibits anti-apoptotic Bcl-XL
  • SRC family kinases in senescent cells

Effects

  • +physical function in IPF (open-label) supports

What the research supports

Improves physical function in IPF (open-label)limited

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
Research protocols only
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodWith a meal containing fat for fat-soluble compounds; otherwise either.
Best formMost evidence is based on the capsule or softgel form.
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Side effects & interactions

Common side effects

  • GI upset

Serious

  • Use only with medical oversight

Medication interactions

QT-prolonging drugssevere

Dasatinib lengthens QT interval.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • NAD+ precursor (NMN or NR)Complementary mitochondrial and sirtuin support.
  • Omega-3Lowers inflammation and supports membrane integrity.

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Quercetin + Dasatinib (D+Q) — Improves physical function in IPF ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "Improves physical function in IPF". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Quercetin + Dasatinib (D+Q) — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Quercetin + Dasatinib (D+Q) — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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