Overview
Anti-inflammatory pair for allergies.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Quercetin mast cell stabilizer; bromelain enhances absorption.
- · Quercetin mast cell stabilizer
- · bromelain enhances absorption
Effects on the body
Organ system effects
Quercetin + Bromelain modulates innate and adaptive immune responses, including cytokine signaling and barrier function.
Evidence-based benefits
Allergy relief
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Autoimmune disease (theoretical immune activation)
- ·Immunosuppressants
Supplement interactions
- Vitamin D3 + K2Foundational immune modulation.
- ZincRequired cofactor for innate and adaptive immune function.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Bromelain bioavailability of polyphenols
Gardner CD, et al.
19 adults
Bromelain enhanced quercetin absorption.
PubMed: Quercetin + Bromelain — Allergy relief
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PubMed: Quercetin + Bromelain — randomized controlled trial
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PubMed: Quercetin + Bromelain — meta-analysis
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PubMed: Quercetin + Bromelain — dose response
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Google Scholar: Quercetin + Bromelain — clinical evidence
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