Overview
Highly bioavailable quercetin glycoside.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Better absorbed than aglycone quercetin.
- · Better absorbed than aglycone quercetin
Effects on the body
Organ system effects
Isoquercetin modulates innate and adaptive immune responses, including cytokine signaling and barrier function.
Isoquercetin supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
Evidence-based benefits
Reduces VTE in cancer
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Autoimmune disease (theoretical immune activation)
- ·Immunosuppressants
Supplement interactions
- Vitamin D3 + K2Foundational immune modulation.
- ZincRequired cofactor for innate and adaptive immune function.
- Omega-3Anti-inflammatory cardiovascular synergy.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Isoquercetin — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Isoquercetin third party tested NSF
CapsulesPre-measured Isoquercetin capsules — easiest for travel and consistent daily dosing without scoops or scales.Isoquercetin capsules
PowderBulk unflavored Isoquercetin powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Isoquercetin powder unflavored
Best sellersMost-purchased Isoquercetin products on Amazon — a quick way to see what's reviewed widely before you commit.Isoquercetin best sellerScientific evidence8Show studiesHide studies
Isoquercetin in cancer VTE
Zwicker JI, et al.
64 cancer patients
Reduced D-dimer and PDI activity.
PubMed: Isoquercetin — Reduces VTE in cancer
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PubMed: Isoquercetin — randomized controlled trial
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PubMed: Isoquercetin — meta-analysis
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PubMed: Isoquercetin — dose response
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Google Scholar: Isoquercetin — clinical evidence
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Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.