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evidence · mechanism · dose
Supplements/Compound

Isoquercetin

Highly bioavailable quercetin glycoside.

Immune FunctionCardiovascular Health

Overview

Highly bioavailable quercetin glycoside.

Natural sources
    Common forms

      Mechanism of action

      Better absorbed than aglycone quercetin.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces VTE in cancer

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Safety & non-supplemental interactions

            Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

            Avoid with these conditions
            • ·Autoimmune disease (theoretical immune activation)
            Avoid / monitor with these medications
            • ·Immunosuppressants

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            500–1000 mg

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Isoquercetin
            Amazon
            Wide selection · fast shipping
            Compound
            Isoquercetin
            iHerb
            Global delivery · curated brands
            Compound
            Isoquercetin
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTJCI Insight · 2019

            Isoquercetin in cancer VTE

            Zwicker JI, et al.

            64 cancer patients

            Key findings

            Reduced D-dimer and PDI activity.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Isoquercetin — Reduces VTE in cancer

            Live PubMed search

            Live results for "Isoquercetin Reduces VTE in cancer" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Isoquercetin and "Reduces VTE in cancer". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Isoquercetin — randomized controlled trial

            Live PubMed search

            Live results for "Isoquercetin randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Isoquercetin and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Isoquercetin — meta-analysis

            Live PubMed search

            Live results for "Isoquercetin meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Isoquercetin and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Isoquercetin — pharmacokinetics

            Live PubMed search

            Live results for "Isoquercetin pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Isoquercetin and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Isoquercetin — safety adverse events

            Live PubMed search

            Live results for "Isoquercetin safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Isoquercetin and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Isoquercetin — dose response

            Live PubMed search

            Live results for "Isoquercetin dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Isoquercetin and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Isoquercetin — clinical evidence

            Live Scholar search

            Cross-database citation index for Isoquercetin as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.