Overview
Phytosterols for cholesterol lowering.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Compete with cholesterol for micellar incorporation.
- · Compete with cholesterol for micellar incorporation
Effects on the body
Organ system effects
Plant Sterols/Stanols supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
Evidence-based benefits
Reduces LDL 8–10%
Moderate evidencePotential side effects
- · Reduced carotenoid absorption
Drug interactions
Supplement interactions
- Omega-3Anti-inflammatory cardiovascular synergy.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Plant sterols meta-analysis
Demonty I, et al.
84 trials
LDL reduction 8.8% at 2.15 g/d.
PubMed: Plant Sterols/Stanols — Reduces LDL 8–10%
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PubMed: Plant Sterols/Stanols — randomized controlled trial
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PubMed: Plant Sterols/Stanols — meta-analysis
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PubMed: Plant Sterols/Stanols — pharmacokinetics
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PubMed: Plant Sterols/Stanols — dose response
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Google Scholar: Plant Sterols/Stanols — clinical evidence
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