Overview
Plant sterols/stanols competitively inhibit cholesterol absorption.
- Vegetable oils
- Nuts
- Fortified foods
- Sitosterol
- Stanol esters
Mechanism of action
Compete with cholesterol for micellar incorporation in gut.
- · Cholesterol absorption inhibition
Effects on the body
Organ system effects
Reduces LDL ~10%.
Evidence-based benefits
Reduces LDL ~10% at 2 g/d
Strong evidencePotential side effects
- · Sitosterolemia in rare genetic disorder
Drug interactions
Supplement interactions
- Omega-3Anti-inflammatory cardiovascular synergy.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Plant sterols and stanols on LDL cholesterol
Demonty I, et al.
Meta-analysis of 84 RCTs of 2 g/d plant sterols.
Mean LDL reduction of 8.8%.
PubMed: Phytosterols (Plant Sterols) — Reduces LDL ~10% at 2 g/d
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