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evidence · mechanism · dose
Supplements/Compound

Partially Hydrolyzed Guar Gum (PHGG)

Soluble fiber for IBS and constipation.

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Overview

Soluble fiber for IBS and constipation.

Natural sources
  • Endogenously produced or biosynthesized molecule
  • Standardized pharmaceutical- or food-grade supplement
  • Combined with cofactors that improve absorption or activity
Common forms
  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Mechanism of action

Fermented to SCFAs without excessive gas.

Pathways
  • · Fermented to SCFAs without excessive gas

Effects on the body

Supports
IBS symptoms

Organ system effects

Digestive / Gut

Partially Hydrolyzed Guar Gum (PHGG) influences gut motility, mucosal integrity, or microbial balance in the GI tract.

Evidence-based benefits

Improves IBS symptoms

Moderate evidence

Potential side effects

Common
  • · Mild bloating
Rare
    Serious

      Drug interactions

      Prescription medications (general)
      Always disclose Partially Hydrolyzed Guar Gum (PHGG) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
      minor

      Supplement interactions

      Pairs well with
      • Multi-strain probiotic
        Supports microbiome diversity and barrier integrity.
      • L-glutamine
        Substrate for enterocyte energy and tight-junction maintenance.
      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      5 g/d
      Best form
      Most evidence is based on the capsule or softgel form.
      Timing
      Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
      With food?
      With a meal containing fat for fat-soluble compounds; otherwise either.

      Where to buy

      Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

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      Scientific evidence8Show studies
      RCTDig Dis Sci · 2002

      PHGG in IBS

      Parisi GC, et al.

      199 IBS patients

      Key findings

      Improved symptoms and bowel habits.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Partially Hydrolyzed Guar Gum (PHGG) — Improves IBS symptoms

      Live PubMed search

      Live results for "Partially Hydrolyzed Guar Gum (PHGG) Improves IBS symptoms" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Partially Hydrolyzed Guar Gum (PHGG) and "Improves IBS symptoms". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Partially Hydrolyzed Guar Gum (PHGG) — randomized controlled trial

      Live PubMed search

      Live results for "Partially Hydrolyzed Guar Gum (PHGG) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Partially Hydrolyzed Guar Gum (PHGG) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Partially Hydrolyzed Guar Gum (PHGG) — meta-analysis

      Live PubMed search

      Live results for "Partially Hydrolyzed Guar Gum (PHGG) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Partially Hydrolyzed Guar Gum (PHGG) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Partially Hydrolyzed Guar Gum (PHGG) — pharmacokinetics

      Live PubMed search

      Live results for "Partially Hydrolyzed Guar Gum (PHGG) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Partially Hydrolyzed Guar Gum (PHGG) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Partially Hydrolyzed Guar Gum (PHGG) — safety adverse events

      Live PubMed search

      Live results for "Partially Hydrolyzed Guar Gum (PHGG) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Partially Hydrolyzed Guar Gum (PHGG) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Partially Hydrolyzed Guar Gum (PHGG) — dose response

      Live PubMed search

      Live results for "Partially Hydrolyzed Guar Gum (PHGG) dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Partially Hydrolyzed Guar Gum (PHGG) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Partially Hydrolyzed Guar Gum (PHGG) — clinical evidence

      Live Scholar search

      Cross-database citation index for Partially Hydrolyzed Guar Gum (PHGG) as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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