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Olive Leaf (Standardized Oleuropein)

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Olive Leaf (Standardized Oleuropein). High-oleuropein extract.

How it works. Oleuropein has antiviral and ACE-inhibitory effects.

What the research supports. 1 graded claims. Strongest: Antiviral and BP lowering (moderate).

How much to take. Typical dose: 500 mg standardized.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Omega-3, CoQ10, Vitamin D3 + K2.

Common forms. Available as Standardized extract capsule, Liquid tincture (alcohol or glycerin), Powdered whole herb, Traditional decoction or tea.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Olive Leaf (Standardized Oleuropein). Anecdotes are not medical advice.

Olive Leaf (Standardized Oleuropein). High-oleuropein extract.

Key compound: oleuropeinC25H32O13 · 540.5 g/mol

What it is

High-oleuropein extract.

Food sources

Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice

Goals

Cardiovascular HealthImmune Function

How it works

Oleuropein has antiviral and ACE-inhibitory effects.

Pathways

  • Oleuropein has antiviral
  • ACE-inhibitory effects

Effects

  • +Antiviral and BP lowering supports

What the research supports

Antiviral and BP loweringmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
500 mg standardized
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither with or without food.
Best formMost evidence is based on the standardized extract capsule form.
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Side effects & interactions

Common side effects

  • GI upset

Medication interactions

Prescription medications (general)minor

Always disclose Olive Leaf (Standardized Oleuropein) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • Omega-3Anti-inflammatory cardiovascular synergy.
  • CoQ10Supports mitochondrial energetics in cardiac tissue.
  • Vitamin D3 + K2Foundational immune modulation.

Common forms

  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Key studies

8 studies cited in total.

PubMed: Olive Leaf (Standardized Oleuropein) — Antiviral and BP lowering ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Olive Leaf (Standardized Oleuropein) and "Antiviral and BP lowering". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Olive Leaf (Standardized Oleuropein) — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Olive Leaf (Standardized Oleuropein) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Olive Leaf (Standardized Oleuropein) — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Olive Leaf (Standardized Oleuropein) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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