Supplement Scholar
Herb

Olive Leaf Extract

Buy on Amazon ↗

Affiliate link: we may earn a commission at no extra cost to you. Disclosures

Olive Leaf Extract. Polyphenol-rich leaf extract for blood pressure and glucose.

How it works. Oleuropein increases NO, inhibits ACE, and improves insulin sensitivity.

What the research supports. 1 graded claims. Strongest: Lowers SBP/DBP in mild hypertension (moderate).

How much to take. Typical dose: 500–1000 mg standardized.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with A high-quality multivitamin, Omega-3 (EPA/DHA).

Common forms. Available as Standardized extract capsule, Liquid tincture (alcohol or glycerin), Powdered whole herb, Traditional decoction or tea.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Olive Leaf Extract. Anecdotes are not medical advice.

Olive Leaf Extract. Polyphenol-rich leaf extract for blood pressure and glucose.

Key compound: oleuropeinC25H32O13 · 540.5 g/mol

What it is

Polyphenol-rich leaf extract for blood pressure and glucose.

Also called

Oleuropein

Food sources

Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice

Goals

Blood Sugar Management

How it works

Oleuropein increases NO, inhibits ACE, and improves insulin sensitivity.

Pathways

  • Oleuropein increases NO, inhibits ACE
  • and improves insulin sensitivity

Effects

  • ↓SBP/DBP in mild hypertension decreases

What the research supports

Lowers SBP/DBP in mild hypertensionmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
500–1000 mg standardized
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodWith food
Best formMost evidence is based on the standardized extract capsule form.
Shop Olive Leaf Extract on Amazon ↗

As an Amazon Associate I earn from qualifying purchases. Look for USP, NSF or Informed Sport seals before you buy.

Side effects & interactions

Common side effects

  • GI upset

Medication interactions

Antihypertensivesmoderate

Additive hypotension.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
  • Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.

Common forms

  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Key studies

8 studies cited in total.

PubMed: Olive Leaf Extract — Lowers SBP/DBP in mild hypertension ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Olive Leaf Extract and "Lowers SBP/DBP in mild hypertension". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Olive Leaf Extract — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Olive Leaf Extract and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Olive Leaf Extract — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Olive Leaf Extract and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

Loading discussion…