Overview
Polyphenol-rich leaf extract for blood pressure and glucose.
- Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
- Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
- Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Mechanism of action
Oleuropein increases NO, inhibits ACE, and improves insulin sensitivity.
- · Oleuropein increases NO, inhibits ACE
- · and improves insulin sensitivity
Effects on the body
Organ system effects
Evidence-based benefits
Lowers SBP/DBP in mild hypertension
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Olive leaf vs captopril in HTN
Susalit E, et al.
8-week DB-RCT in 232 stage-1 HTN patients.
Olive leaf 500 mg bid equivalent to captopril 12.5–25 mg bid.
PubMed: Olive Leaf Extract — Lowers SBP/DBP in mild hypertension
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PubMed: Olive Leaf Extract — randomized controlled trial
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PubMed: Olive Leaf Extract — meta-analysis
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PubMed: Olive Leaf Extract — pharmacokinetics
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PubMed: Olive Leaf Extract — dose response
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Google Scholar: Olive Leaf Extract — clinical evidence
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