Overview
Grapefruit precursor to naringenin.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Bitter glycoside metabolized to naringenin.
- · Bitter glycoside metabolized to naringenin
Effects on the body
Organ system effects
Naringin affects hepatic insulin sensitivity, lipid handling, or glucose disposal.
Evidence-based benefits
Antioxidant
Moderate evidencePotential side effects
- · CYP3A4 inhibition
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Scientific evidence8Show studiesHide studies
Naringin hypercholesterolemia
Jung UJ, et al.
60 hypercholesterolemic patients
Reduced LDL 17% at 400 mg.
PubMed: Naringin — Antioxidant
Live PubMed search
Live results for "Naringin Antioxidant" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Naringin and "Antioxidant". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Naringin — randomized controlled trial
Live PubMed search
Live results for "Naringin randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Naringin and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Naringin — meta-analysis
Live PubMed search
Live results for "Naringin meta-analysis" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Naringin and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Naringin — pharmacokinetics
Live PubMed search
Live results for "Naringin pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Naringin and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Naringin — safety adverse events
Live PubMed search
Live results for "Naringin safety adverse events" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Naringin and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Naringin — dose response
Live PubMed search
Live results for "Naringin dose response" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Naringin and "dose response". Filter by RCT, meta-analysis, or year on the results page.
Google Scholar: Naringin — clinical evidence
Live Scholar search
Cross-database citation index for Naringin as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.