Overview
Erythrina mulungu bark for anxiety relief.
- Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
- Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
- Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Mechanism of action
Erythravine alkaloids modulate GABA-A receptors.
- · Erythravine alkaloids modulate GABA-A receptors
Effects on the body
Organ system effects
Mulungu modulates monoaminergic and GABAergic tone relevant to mood and anxiety regulation.
Evidence-based benefits
Reduces anxiety
Moderate evidencePotential side effects
- · Sedation
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Mulungu anxiolytic effects
Onusic GM, et al.
Erythrina extract in rodent anxiety models
Comparable to diazepam in elevated plus-maze.
PubMed: Mulungu — Reduces anxiety
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PubMed: Mulungu — randomized controlled trial
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PubMed: Mulungu — meta-analysis
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PubMed: Mulungu — pharmacokinetics
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PubMed: Mulungu — safety adverse events
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PubMed: Mulungu — dose response
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Google Scholar: Mulungu — clinical evidence
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