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Supplements/Compound

Monolaurin

aka Lauricidin

Coconut-derived monoglyceride with antimicrobial properties against enveloped viruses.

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Overview

Coconut-derived monoglyceride with antimicrobial properties against enveloped viruses.

Natural sources
  • Coconut oil derivative
Common forms
  • Monolaurin pellets

Mechanism of action

Disrupts lipid envelopes of viruses and gram+ bacteria.

Pathways
  • · Lipid envelope disruption

Effects on the body

Supports
Antiviral activity (in vitro)

Organ system effects

Immune System

Monolaurin modulates innate and adaptive immune responses, including cytokine signaling and barrier function.

Evidence-based benefits

In vitro antiviral; limited human data

Limited evidence

Potential side effects

Common
  • · GI upset
Rare
    Serious

      Drug interactions

      Prescription medications (general)
      Always disclose Monolaurin use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
      minor

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid with these conditions
      • ·Autoimmune disease (theoretical immune activation)
      Avoid / monitor with these medications
      • ·Immunosuppressants

      Supplement interactions

      Pairs well with
      • Vitamin D3 + K2
        Foundational immune modulation.
      • Zinc
        Required cofactor for innate and adaptive immune function.
      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      1500–3000 mg/d
      Best form
      Most evidence is based on the monolaurin pellets form.
      Timing
      Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
      With food?
      With a meal containing fat for fat-soluble compounds; otherwise either.

      Where to buy

      Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Scientific evidence8Show studies
      In vitroPLoS One · 2012

      Monolaurin antimicrobial activity

      Schlievert PM, Peterson ML

      In vitro testing against bacterial pathogens.

      Key findings

      Effective against gram-positive pathogens including Staph aureus.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Monolaurin — In vitro antiviral; limited human data

      Live PubMed search

      Live results for "Monolaurin In vitro antiviral; limited human data" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Monolaurin and "In vitro antiviral; limited human data". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Monolaurin — randomized controlled trial

      Live PubMed search

      Live results for "Monolaurin randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Monolaurin and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Monolaurin — meta-analysis

      Live PubMed search

      Live results for "Monolaurin meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Monolaurin and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Monolaurin — pharmacokinetics

      Live PubMed search

      Live results for "Monolaurin pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Monolaurin and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Monolaurin — safety adverse events

      Live PubMed search

      Live results for "Monolaurin safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Monolaurin and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Monolaurin — dose response

      Live PubMed search

      Live results for "Monolaurin dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Monolaurin and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Monolaurin — clinical evidence

      Live Scholar search

      Cross-database citation index for Monolaurin as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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