Overview
Mitochondria-targeted ubiquinone (CoQ10 analog).
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Triphenylphosphonium cation concentrates in mitochondria.
- · Triphenylphosphonium cation concentrates in mitochondria
Effects on the body
Organ system effects
MitoQ acts on hallmarks of aging including oxidative stress, mitochondrial dysfunction, and senescence signaling.
MitoQ supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
Evidence-based benefits
Improves vascular function in older adults
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Supplement interactions
- NAD+ precursor (NMN or NR)Complementary mitochondrial and sirtuin support.
- Omega-3Lowers inflammation and supports membrane integrity.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
MitoQ vascular function
Rossman MJ, et al.
20 older adults
Improved endothelial function 42%.
PubMed: MitoQ — Improves vascular function in older adults
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PubMed: MitoQ — randomized controlled trial
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PubMed: MitoQ — dose response
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Google Scholar: MitoQ — clinical evidence
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