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evidence · mechanism · dose
Supplements/Compound

MCT C8 (Caprylic Acid)

Pure C8 medium-chain triglyceride for ketone production.

Brain & Cognitive

Overview

Pure C8 medium-chain triglyceride for ketone production.

Natural sources
    Common forms

      Mechanism of action

      Rapidly oxidized to ketones via liver beta-oxidation.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Raises blood ketones

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        • · Diarrhea
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            10–30 g

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

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            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTJ Nutr · 2017

            C8 MCT ketogenesis

            Vandenberghe C, et al.

            Healthy adults

            Key findings

            C8 produced 3-fold higher ketones than C8:C10 blend.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: MCT C8 (Caprylic Acid) — Raises blood ketones

            Live PubMed search

            Live results for "MCT C8 (Caprylic Acid) Raises blood ketones" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching MCT C8 (Caprylic Acid) and "Raises blood ketones". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: MCT C8 (Caprylic Acid) — randomized controlled trial

            Live PubMed search

            Live results for "MCT C8 (Caprylic Acid) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching MCT C8 (Caprylic Acid) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: MCT C8 (Caprylic Acid) — meta-analysis

            Live PubMed search

            Live results for "MCT C8 (Caprylic Acid) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching MCT C8 (Caprylic Acid) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: MCT C8 (Caprylic Acid) — pharmacokinetics

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            Live results for "MCT C8 (Caprylic Acid) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching MCT C8 (Caprylic Acid) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: MCT C8 (Caprylic Acid) — safety adverse events

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            Live results for "MCT C8 (Caprylic Acid) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

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            Opens current human and preclinical literature matching MCT C8 (Caprylic Acid) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: MCT C8 (Caprylic Acid) — dose response

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            Live results for "MCT C8 (Caprylic Acid) dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching MCT C8 (Caprylic Acid) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: MCT C8 (Caprylic Acid) — clinical evidence

            Live Scholar search

            Cross-database citation index for MCT C8 (Caprylic Acid) as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.