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Compound

Marine Collagen (Extra)

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Marine Collagen (Extra). Fish-derived type I collagen with high digestibility.

How it works. Hydrolyzed dipeptides (Pro-Hyp, Hyp-Gly) stimulate fibroblast collagen synthesis.

What the research supports. 1 graded claims. Strongest: Improves skin elasticity and hydration (strong).

How much to take. Typical dose: 2.5–10 g.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Collagen peptides, Vitamin C.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Marine Collagen (Extra). Anecdotes are not medical advice.

Marine Collagen (Extra). Fish-derived type I collagen with high digestibility.

Key compound: prolylhydroxyprolineC10H16N2O4 · 228.24 g/mol

What it is

Fish-derived type I collagen with high digestibility.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

How it works

Hydrolyzed dipeptides (Pro-Hyp, Hyp-Gly) stimulate fibroblast collagen synthesis.

Pathways

  • Hydrolyzed dipeptides (Pro-Hyp, Hyp-Gly) stimulate fibroblast collagen synthesis

Effects

  • +skin elasticity and hydration supports

What the research supports

Improves skin elasticity and hydrationstrong

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
2.5–10 g
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither
Best formMost evidence is based on the capsule or softgel form.
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Side effects & interactions

Common side effects

  • Mild GI

Medication interactions

Prescription medications (general)minor

Always disclose Marine Collagen (Extra) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • Collagen peptidesProvides amino acid substrate for connective tissue synthesis.
  • Vitamin CRequired cofactor for collagen hydroxylation.

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Marine Collagen (Extra) — Improves skin elasticity and hydration ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Marine Collagen (Extra) and "Improves skin elasticity and hydration". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Marine Collagen (Extra) — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Marine Collagen (Extra) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Marine Collagen (Extra) — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Marine Collagen (Extra) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

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