Overview
Active magnolia biphenol.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
GABA-A receptor modulator.
- · GABA-A receptor modulator
Effects on the body
Organ system effects
Magnolol modulates monoaminergic and GABAergic tone relevant to mood and anxiety regulation.
Evidence-based benefits
Anxiolytic
Moderate evidencePotential side effects
- · Drowsiness
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Magnolol pharmacology
Lin YR, et al.
Mechanistic review
Anxiolytic without dependence.
PubMed: Magnolol — Anxiolytic
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PubMed: Magnolol — randomized controlled trial
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PubMed: Magnolol — meta-analysis
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PubMed: Magnolol — pharmacokinetics
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PubMed: Magnolol — safety adverse events
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PubMed: Magnolol — dose response
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Google Scholar: Magnolol — clinical evidence
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