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evidence · mechanism · dose
Supplements/Compound

Magnolol

Active magnolia biphenol.

Mood & Anxiety

Overview

Active magnolia biphenol.

Natural sources
    Common forms

      Mechanism of action

      GABA-A receptor modulator.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Anxiolytic

        Moderate evidence

        Potential side effects

        Common
        • · Drowsiness
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            200 mg

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Magnolol
            Amazon
            Wide selection · fast shipping
            Compound
            Magnolol
            iHerb
            Global delivery · curated brands
            Compound
            Magnolol
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            Systematic reviewNeuropharmacology · 2009

            Magnolol pharmacology

            Lin YR, et al.

            Mechanistic review

            Key findings

            Anxiolytic without dependence.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Magnolol — Anxiolytic

            Live PubMed search

            Live results for "Magnolol Anxiolytic" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Magnolol and "Anxiolytic". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Magnolol — randomized controlled trial

            Live PubMed search

            Live results for "Magnolol randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Magnolol and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Magnolol — meta-analysis

            Live PubMed search

            Live results for "Magnolol meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Magnolol and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Magnolol — pharmacokinetics

            Live PubMed search

            Live results for "Magnolol pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Magnolol and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Magnolol — safety adverse events

            Live PubMed search

            Live results for "Magnolol safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Magnolol and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Magnolol — dose response

            Live PubMed search

            Live results for "Magnolol dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Magnolol and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Magnolol — clinical evidence

            Live Scholar search

            Cross-database citation index for Magnolol as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.