Overview
Earthworm-derived fibrinolytic enzyme complex.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Directly digests fibrin and activates plasminogen; lowers blood viscosity.
- · Directly digests fibrin
- · activates plasminogen
- · lowers blood viscosity
Effects on the body
Organ system effects
Lumbrokinase supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
Evidence-based benefits
Improves outcomes in acute ischemic stroke (Chinese trials)
Moderate evidencePotential side effects
- · GI upset
- · Bleeding risk
Drug interactions
Supplement interactions
- Omega-3Anti-inflammatory cardiovascular synergy.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Lumbrokinase — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Lumbrokinase third party tested NSF
CapsulesPre-measured Lumbrokinase capsules — easiest for travel and consistent daily dosing without scoops or scales.Lumbrokinase capsules
PowderBulk unflavored Lumbrokinase powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Lumbrokinase powder unflavored
Best sellersMost-purchased Lumbrokinase products on Amazon — a quick way to see what's reviewed widely before you commit.Lumbrokinase best sellerScientific evidence8Show studiesHide studies
Lumbrokinase in ischemic stroke
Cao YJ, et al.
Meta-analysis of 14 RCTs in acute ischemic stroke.
Improved neurological scores vs control with acceptable bleeding profile.
PubMed: Lumbrokinase — Improves outcomes in acute ischemic stroke
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PubMed: Lumbrokinase — dose response
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Google Scholar: Lumbrokinase — clinical evidence
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