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evidence · mechanism · dose
Supplements/Compound

L. helveticus R0052

Psychobiotic blend component for mood.

Mood & Anxiety

Overview

Psychobiotic blend component for mood.

Natural sources
    Common forms

      Mechanism of action

      Modulates gut-brain axis.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces anxiety

        Moderate evidence

        Potential side effects

        Common
        • · Mild GI
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            3 billion CFU

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            L. helveticu…
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            Compound
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            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTBr J Nutr · 2011

            Probiotic mood RCT

            Messaoudi M, et al.

            55 healthy adults

            Key findings

            Reduced anxiety and depression scores.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: L. helveticus R0052 — Reduces anxiety

            Live PubMed search

            Live results for "L. helveticus R0052 Reduces anxiety" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching L. helveticus R0052 and "Reduces anxiety". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: L. helveticus R0052 — randomized controlled trial

            Live PubMed search

            Live results for "L. helveticus R0052 randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching L. helveticus R0052 and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: L. helveticus R0052 — meta-analysis

            Live PubMed search

            Live results for "L. helveticus R0052 meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching L. helveticus R0052 and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: L. helveticus R0052 — pharmacokinetics

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            Live results for "L. helveticus R0052 pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching L. helveticus R0052 and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: L. helveticus R0052 — safety adverse events

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            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: L. helveticus R0052 — dose response

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            Key findings

            Opens current human and preclinical literature matching L. helveticus R0052 and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: L. helveticus R0052 — clinical evidence

            Live Scholar search

            Cross-database citation index for L. helveticus R0052 as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.