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Iberogast (STW-5)

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Iberogast (STW-5). Nine-herb European tincture for functional dyspepsia and IBS.

How it works. Region-specific modulation of GI smooth muscle tone and visceral hypersensitivity.

What the research supports. 1 graded claims. Strongest: Improves dyspepsia and IBS symptoms (strong).

How much to take. Typical dose: 20 drops tid.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with A high-quality multivitamin, Omega-3 (EPA/DHA).

Common forms. Available as Standardized extract capsule, Liquid tincture (alcohol or glycerin), Powdered whole herb, Traditional decoction or tea.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Iberogast (STW-5). Anecdotes are not medical advice.

Iberogast (STW-5). Nine-herb European tincture for functional dyspepsia and IBS.

No single structure

What it is

Nine-herb European tincture for functional dyspepsia and IBS.

Food sources

Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice

How it works

Region-specific modulation of GI smooth muscle tone and visceral hypersensitivity.

Pathways

  • Region-specific modulation of GI smooth muscle tone
  • visceral hypersensitivity

Effects

  • +dyspepsia and IBS symptoms supports

What the research supports

Improves dyspepsia and IBS symptomsstrong

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
20 drops tid
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodWith meals
Best formMost evidence is based on the standardized extract capsule form.
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Side effects & interactions

Common side effects

  • Mild GI symptoms

Medication interactions

Prescription medications (general)minor

Always disclose Iberogast (STW-5) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
  • Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.

Common forms

  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Key studies

8 studies cited in total.

PubMed: Iberogast (STW-5) — Improves dyspepsia and IBS symptoms ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Iberogast (STW-5) and "Improves dyspepsia and IBS symptoms". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Iberogast (STW-5) — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Iberogast (STW-5) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Iberogast (STW-5) — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Iberogast (STW-5) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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