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evidence · mechanism · dose
Supplements/Herb

Iberogast (STW-5)

Nine-herb European tincture for functional dyspepsia and IBS.

Overview

Nine-herb European tincture for functional dyspepsia and IBS.

Natural sources
    Common forms

      Mechanism of action

      Region-specific modulation of GI smooth muscle tone and visceral hypersensitivity.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves dyspepsia and IBS symptoms

        Strong evidence

        Potential side effects

        Common
        • · Mild GI symptoms
        Rare
        • · Idiosyncratic hepatotoxicity
        Serious

          Drug interactions

          No notable interactions reported.

          Safety & non-supplemental interactions

          Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

          Avoid if you are
          • ·Pregnant or breastfeeding (insufficient safety data)
          • ·Children under 18 (unless directed by a clinician)

          Supplement interactions

          Pairs well with

          None listed.

          Avoid combining with

          No specific avoidances listed.

          Dosing & bioavailability

          Typical dose
          20 drops tid
          With food?
          With meals

          Where to buy

          Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

          Herb
          Iberogast (S…
          Amazon
          Wide selection · fast shipping
          Herb
          Iberogast (S…
          iHerb
          Global delivery · curated brands
          Herb
          Iberogast (S…
          Thorne
          Practitioner-grade · NSF tested

          Scientific evidence (8)

          RCTAliment Pharmacol Ther · 2004

          STW-5 vs placebo in functional dyspepsia

          Madisch A, et al.

          8-week DB-RCT in 315 patients.

          Key findings

          Significantly improved GI symptom score vs placebo.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Iberogast (STW-5) — Improves dyspepsia and IBS symptoms

          Live PubMed search

          Live results for "Iberogast (STW-5) Improves dyspepsia and IBS symptoms" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Iberogast (STW-5) and "Improves dyspepsia and IBS symptoms". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Iberogast (STW-5) — randomized controlled trial

          Live PubMed search

          Live results for "Iberogast (STW-5) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Iberogast (STW-5) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Iberogast (STW-5) — meta-analysis

          Live PubMed search

          Live results for "Iberogast (STW-5) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Iberogast (STW-5) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Iberogast (STW-5) — pharmacokinetics

          Live PubMed search

          Live results for "Iberogast (STW-5) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Iberogast (STW-5) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Iberogast (STW-5) — safety adverse events

          Live PubMed search

          Live results for "Iberogast (STW-5) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Iberogast (STW-5) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Iberogast (STW-5) — dose response

          Live PubMed search

          Live results for "Iberogast (STW-5) dose response" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Iberogast (STW-5) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewGoogle Scholar · 1970

          Google Scholar: Iberogast (STW-5) — clinical evidence

          Live Scholar search

          Cross-database citation index for Iberogast (STW-5) as it relates to "clinical evidence".

          Key findings

          Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

          Open study
          Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.