SYS ONLINE
Supplements/Compound

Hydroxytyrosol

Olive polyphenol for cardiovascular health.

Overview

Olive polyphenol for cardiovascular health.

Natural sources
    Common forms

      Mechanism of action

      Potent antioxidant; LDL oxidation inhibitor.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces LDL oxidation

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            15–30 mg

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Scientific evidence (8)

            Systematic reviewEFSA Journal · 2011

            EFSA olive oil polyphenols claim

            EFSA Panel

            Mechanistic review

            Key findings

            Approved health claim: 5 mg/day hydroxytyrosol protects LDL.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Hydroxytyrosol — Reduces LDL oxidation

            Live PubMed search

            Live results for "Hydroxytyrosol Reduces LDL oxidation" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Hydroxytyrosol and "Reduces LDL oxidation". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Hydroxytyrosol — randomized controlled trial

            Live PubMed search

            Live results for "Hydroxytyrosol randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Hydroxytyrosol and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Hydroxytyrosol — meta-analysis

            Live PubMed search

            Live results for "Hydroxytyrosol meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Hydroxytyrosol and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Hydroxytyrosol — pharmacokinetics

            Live PubMed search

            Live results for "Hydroxytyrosol pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Hydroxytyrosol and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Hydroxytyrosol — safety adverse events

            Live PubMed search

            Live results for "Hydroxytyrosol safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Hydroxytyrosol and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Hydroxytyrosol — dose response

            Live PubMed search

            Live results for "Hydroxytyrosol dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Hydroxytyrosol and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Hydroxytyrosol — clinical evidence

            Live Scholar search

            Cross-database citation index for Hydroxytyrosol as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.