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evidence · mechanism · dose
Supplements/Compound

Glucomannan (Konjac)

Viscous soluble fiber that promotes satiety and lowers LDL.

Blood Sugar Management

Overview

Viscous soluble fiber that promotes satiety and lowers LDL.

Natural sources
    Common forms

      Mechanism of action

      Expands in stomach to slow gastric emptying; binds bile acids.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Modest weight loss as part of hypocaloric diet

        Moderate evidence

        Lowers LDL ~10%

        Strong evidence

        Potential side effects

        Common
        • · Bloating
        • · Choking risk if dry
        Rare
          Serious
          • · Esophageal obstruction if not taken with water

          Drug interactions

          Oral medications
          Take 1 h apart due to absorption interference.
          moderate

          Supplement interactions

          Pairs well with

          None listed.

          Avoid combining with

          No specific avoidances listed.

          Dosing & bioavailability

          Typical dose
          1 g tid with 250 mL water
          With food?
          Before meals

          Where to buy

          Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

          Compound
          Glucomannan …
          Amazon
          Wide selection · fast shipping
          Compound
          Glucomannan …
          iHerb
          Global delivery · curated brands
          Compound
          Glucomannan …
          Thorne
          Practitioner-grade · NSF tested

          Scientific evidence (9)

          RCTPhytother Res · 2008

          Glucomannan in overweight adults

          Vasques CA, et al.

          16-week DB-RCT in 58 overweight adults.

          Key findings

          Modest weight reduction and improved lipid profile.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Glucomannan (Konjac) — Modest weight loss as part of hypocaloric diet

          Live PubMed search

          Live results for "Glucomannan (Konjac) Modest weight loss as part of hypocaloric diet" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Glucomannan (Konjac) and "Modest weight loss as part of hypocaloric diet". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Glucomannan (Konjac) — Lowers LDL ~10%

          Live PubMed search

          Live results for "Glucomannan (Konjac) Lowers LDL ~10%" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Glucomannan (Konjac) and "Lowers LDL ~10%". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Glucomannan (Konjac) — randomized controlled trial

          Live PubMed search

          Live results for "Glucomannan (Konjac) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Glucomannan (Konjac) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Glucomannan (Konjac) — meta-analysis

          Live PubMed search

          Live results for "Glucomannan (Konjac) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Glucomannan (Konjac) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Glucomannan (Konjac) — pharmacokinetics

          Live PubMed search

          Live results for "Glucomannan (Konjac) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Glucomannan (Konjac) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Glucomannan (Konjac) — safety adverse events

          Live PubMed search

          Live results for "Glucomannan (Konjac) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Glucomannan (Konjac) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Glucomannan (Konjac) — dose response

          Live PubMed search

          Live results for "Glucomannan (Konjac) dose response" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Glucomannan (Konjac) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewGoogle Scholar · 1970

          Google Scholar: Glucomannan (Konjac) — clinical evidence

          Live Scholar search

          Cross-database citation index for Glucomannan (Konjac) as it relates to "clinical evidence".

          Key findings

          Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

          Open study
          Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.