Overview
Viscous soluble fiber that promotes satiety and lowers LDL.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Expands in stomach to slow gastric emptying; binds bile acids.
- · Expands in stomach to slow gastric emptying
- · binds bile acids
Effects on the body
Organ system effects
Evidence-based benefits
Modest weight loss as part of hypocaloric diet
Moderate evidenceLowers LDL ~10%
Strong evidencePotential side effects
- · Bloating
- · Choking risk if dry
- · Esophageal obstruction if not taken with water
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence9Show studiesHide studies
Glucomannan in overweight adults
Vasques CA, et al.
16-week DB-RCT in 58 overweight adults.
Modest weight reduction and improved lipid profile.
PubMed: Glucomannan (Konjac) — Modest weight loss as part of hypocaloric diet
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PubMed: Glucomannan (Konjac) — Lowers LDL ~10%
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PubMed: Glucomannan (Konjac) — randomized controlled trial
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PubMed: Glucomannan (Konjac) — meta-analysis
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PubMed: Glucomannan (Konjac) — pharmacokinetics
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PubMed: Glucomannan (Konjac) — dose response
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Google Scholar: Glucomannan (Konjac) — clinical evidence
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