SYS ONLINE
SUPPLEMENT_SCHOLAR
evidence · mechanism · dose
Supplements/Herb

Ginkgo Biloba

Vasoactive herb studied for cognition in the elderly and tinnitus.

Brain & CognitiveHealthy Aging

Overview

Vasoactive herb studied for cognition in the elderly and tinnitus.

Natural sources
  • Ginkgo biloba leaf
Common forms
  • EGb 761 (24% flavonoids, 6% terpenes)

Mechanism of action

Antioxidant flavonoids and PAF-antagonist terpenes; improves microcirculation.

Pathways
  • · PAF antagonism
  • · Microcirculation

Effects on the body

Supports
Cerebral blood flow

Organ system effects

Brain & CNS

Modest cognitive benefit in dementia.

Evidence-based benefits

Modest cognitive improvement in dementia

Moderate evidence

Reduces vertigo and tinnitus (small effect)

Limited evidence

Potential side effects

Common
  • · Headache
  • · GI upset
Rare
    Serious
    • · Bleeding (case reports)

    Drug interactions

    Anticoagulants / antiplatelets
    Bleeding risk.
    severe
    Anticonvulsants
    May lower seizure threshold.
    moderate

    Safety & non-supplemental interactions

    Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

    Avoid if you are
    • ·Pregnant or breastfeeding (insufficient safety data)
    • ·Children under 18 (unless directed by a clinician)

    Supplement interactions

    Pairs well with

    None listed.

    Avoid combining with

    No specific avoidances listed.

    Dosing & bioavailability

    Typical dose
    120–240 mg EGb 761 divided

    Where to buy

    Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

    Herb
    Ginkgo Biloba
    Amazon
    Wide selection · fast shipping
    Herb
    Ginkgo Biloba
    iHerb
    Global delivery · curated brands
    Herb
    Ginkgo Biloba
    Thorne
    Practitioner-grade · NSF tested

    Scientific evidence (9)

    Meta-analysisCochrane Database · 2009

    Ginkgo biloba for cognitive impairment and dementia

    Birks J, Grimley Evans J

    Cochrane review of 36 RCTs of Ginkgo.

    Key findings

    Inconsistent results; possible benefit in dementia at 240 mg/d.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Ginkgo Biloba — Modest cognitive improvement in dementia

    Live PubMed search

    Live results for "Ginkgo Biloba Modest cognitive improvement in dementia" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Ginkgo Biloba and "Modest cognitive improvement in dementia". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Ginkgo Biloba — Reduces vertigo and tinnitus

    Live PubMed search

    Live results for "Ginkgo Biloba Reduces vertigo and tinnitus" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Ginkgo Biloba and "Reduces vertigo and tinnitus". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Ginkgo Biloba — randomized controlled trial

    Live PubMed search

    Live results for "Ginkgo Biloba randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Ginkgo Biloba and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Ginkgo Biloba — meta-analysis

    Live PubMed search

    Live results for "Ginkgo Biloba meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Ginkgo Biloba and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Ginkgo Biloba — pharmacokinetics

    Live PubMed search

    Live results for "Ginkgo Biloba pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Ginkgo Biloba and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Ginkgo Biloba — safety adverse events

    Live PubMed search

    Live results for "Ginkgo Biloba safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Ginkgo Biloba and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Ginkgo Biloba — dose response

    Live PubMed search

    Live results for "Ginkgo Biloba dose response" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Ginkgo Biloba and "dose response". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewGoogle Scholar · 1970

    Google Scholar: Ginkgo Biloba — clinical evidence

    Live Scholar search

    Cross-database citation index for Ginkgo Biloba as it relates to "clinical evidence".

    Key findings

    Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

    Open study
    Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.