Overview
Short-chain prebiotic.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Fermented by Bifidobacteria.
- · Fermented by Bifidobacteria
Effects on the body
Organ system effects
FOS (Fructooligosaccharides) influences gut motility, mucosal integrity, or microbial balance in the GI tract.
Evidence-based benefits
Improves stool consistency
Moderate evidencePotential side effects
- · Bloating
- · Gas
Drug interactions
Supplement interactions
- Multi-strain probioticSupports microbiome diversity and barrier integrity.
- L-glutamineSubstrate for enterocyte energy and tight-junction maintenance.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
FOS for constipation
Roberfroid M
Mechanistic review
Bifidogenic and laxative effects.
PubMed: FOS (Fructooligosaccharides) — Improves stool consistency
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PubMed: FOS (Fructooligosaccharides) — randomized controlled trial
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PubMed: FOS (Fructooligosaccharides) — meta-analysis
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PubMed: FOS (Fructooligosaccharides) — pharmacokinetics
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PubMed: FOS (Fructooligosaccharides) — safety adverse events
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PubMed: FOS (Fructooligosaccharides) — dose response
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Google Scholar: FOS (Fructooligosaccharides) — clinical evidence
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Cross-database citation index for FOS (Fructooligosaccharides) as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.