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evidence · mechanism · dose
Supplements/Compound

FODZYME (α-galactosidase + lactase)

Enzyme blend that breaks down FODMAPs at the meal level.

Overview

Enzyme blend that breaks down FODMAPs at the meal level.

Natural sources
    Common forms

      Mechanism of action

      Cleaves fructans, galactans, and lactose before fermentation in the colon.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces FODMAP-induced symptoms

        Limited evidence

        Potential side effects

        Common
          Rare
            Serious

              Drug interactions

              No notable interactions reported.

              Supplement interactions

              Pairs well with

              None listed.

              Avoid combining with

              No specific avoidances listed.

              Dosing & bioavailability

              Typical dose
              1 scoop per high-FODMAP meal
              With food?
              With meals

              Where to buy

              Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

              Compound
              FODZYME (α-g…
              Amazon
              Wide selection · fast shipping
              Compound
              FODZYME (α-g…
              iHerb
              Global delivery · curated brands
              Compound
              FODZYME (α-g…
              Thorne
              Practitioner-grade · NSF tested

              Scientific evidence (8)

              RCTAliment Pharmacol Ther · 2007

              α-galactosidase in IBS with gas

              Di Stefano M, et al.

              Crossover RCT in 8 IBS patients.

              Key findings

              Reduced flatus and pain after legume meals.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: FODZYME (α-galactosidase + lactase) — Reduces FODMAP-induced symptoms

              Live PubMed search

              Live results for "FODZYME (α-galactosidase + lactase) Reduces FODMAP-induced symptoms" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching FODZYME (α-galactosidase + lactase) and "Reduces FODMAP-induced symptoms". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: FODZYME (α-galactosidase + lactase) — randomized controlled trial

              Live PubMed search

              Live results for "FODZYME (α-galactosidase + lactase) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching FODZYME (α-galactosidase + lactase) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: FODZYME (α-galactosidase + lactase) — meta-analysis

              Live PubMed search

              Live results for "FODZYME (α-galactosidase + lactase) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching FODZYME (α-galactosidase + lactase) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: FODZYME (α-galactosidase + lactase) — pharmacokinetics

              Live PubMed search

              Live results for "FODZYME (α-galactosidase + lactase) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching FODZYME (α-galactosidase + lactase) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: FODZYME (α-galactosidase + lactase) — safety adverse events

              Live PubMed search

              Live results for "FODZYME (α-galactosidase + lactase) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching FODZYME (α-galactosidase + lactase) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: FODZYME (α-galactosidase + lactase) — dose response

              Live PubMed search

              Live results for "FODZYME (α-galactosidase + lactase) dose response" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching FODZYME (α-galactosidase + lactase) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewGoogle Scholar · 1970

              Google Scholar: FODZYME (α-galactosidase + lactase) — clinical evidence

              Live Scholar search

              Cross-database citation index for FODZYME (α-galactosidase + lactase) as it relates to "clinical evidence".

              Key findings

              Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

              Open study
              Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.