SYS ONLINE
SUPPLEMENT_SCHOLAR
evidence · mechanism · dose
Supplements/Fatty Acid

Flax Seed Oil (ALA)

Alpha-linolenic acid omega-3.

Cardiovascular Health

Overview

Alpha-linolenic acid omega-3.

Natural sources
    Common forms

      Mechanism of action

      ALA converts inefficiently to EPA.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Modest cardiovascular effects

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            1 tbsp

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Fatty Acid
            Flax Seed Oi…
            Amazon
            Wide selection · fast shipping
            Fatty Acid
            Flax Seed Oi…
            iHerb
            Global delivery · curated brands
            Fatty Acid
            Flax Seed Oi…
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            Meta-analysisAm J Clin Nutr · 2009

            Flax for cardiovascular

            Pan A, et al.

            27 RCTs

            Key findings

            Reduced total and LDL cholesterol.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Flax Seed Oil (ALA) — Modest cardiovascular effects

            Live PubMed search

            Live results for "Flax Seed Oil (ALA) Modest cardiovascular effects" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Flax Seed Oil (ALA) and "Modest cardiovascular effects". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Flax Seed Oil (ALA) — randomized controlled trial

            Live PubMed search

            Live results for "Flax Seed Oil (ALA) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Flax Seed Oil (ALA) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Flax Seed Oil (ALA) — meta-analysis

            Live PubMed search

            Live results for "Flax Seed Oil (ALA) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Flax Seed Oil (ALA) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Flax Seed Oil (ALA) — pharmacokinetics

            Live PubMed search

            Live results for "Flax Seed Oil (ALA) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Flax Seed Oil (ALA) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Flax Seed Oil (ALA) — safety adverse events

            Live PubMed search

            Live results for "Flax Seed Oil (ALA) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Flax Seed Oil (ALA) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Flax Seed Oil (ALA) — dose response

            Live PubMed search

            Live results for "Flax Seed Oil (ALA) dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Flax Seed Oil (ALA) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Flax Seed Oil (ALA) — clinical evidence

            Live Scholar search

            Cross-database citation index for Flax Seed Oil (ALA) as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.