Overview
Alpha-linolenic acid omega-3.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
ALA converts inefficiently to EPA.
- · ALA converts inefficiently to EPA
Effects on the body
Organ system effects
Flax Seed Oil (ALA) supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
Evidence-based benefits
Modest cardiovascular effects
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Supplement interactions
- Omega-3Anti-inflammatory cardiovascular synergy.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Flax for cardiovascular
Pan A, et al.
27 RCTs
Reduced total and LDL cholesterol.
PubMed: Flax Seed Oil (ALA) — Modest cardiovascular effects
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PubMed: Flax Seed Oil (ALA) — randomized controlled trial
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PubMed: Flax Seed Oil (ALA) — meta-analysis
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PubMed: Flax Seed Oil (ALA) — pharmacokinetics
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PubMed: Flax Seed Oil (ALA) — dose response
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Google Scholar: Flax Seed Oil (ALA) — clinical evidence
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