Overview
New Zealand pine bark extract.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Procyanidins with antioxidant and anti-inflammatory effects.
- · Procyanidins with antioxidant
- · anti-inflammatory effects
Effects on the body
Organ system effects
Enzogenol acts on central nervous system targets implicated in attention, memory, and neuroprotection.
Enzogenol supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
Evidence-based benefits
Improves cognitive function
Moderate evidencePotential side effects
- · Well tolerated
Drug interactions
Supplement interactions
- Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
- Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.
- Omega-3Anti-inflammatory cardiovascular synergy.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Enzogenol for cognition
Pipingas A, et al.
42 older adults
Improved spatial working memory.
PubMed: Enzogenol — Improves cognitive function
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PubMed: Enzogenol — randomized controlled trial
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PubMed: Enzogenol — meta-analysis
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PubMed: Enzogenol — dose response
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Google Scholar: Enzogenol — clinical evidence
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