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Compound

Ellagic Acid

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Ellagic Acid. Ellagitannin hydrolysis product.

How it works. Antioxidant; metabolized to urolithins.

What the research supports. 1 graded claims. Strongest: Antioxidant (moderate).

How much to take. Typical dose: 100 mg.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with NAD+ precursor (NMN or NR), Omega-3.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Ellagic Acid. Anecdotes are not medical advice.

Ellagic Acid. Ellagitannin hydrolysis product.

Molecular structureC14H6O8 · 302.19 g/mol

What it is

Ellagitannin hydrolysis product.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

How it works

Antioxidant; metabolized to urolithins.

Pathways

  • Antioxidant
  • metabolized to urolithins

Effects

  • +Antioxidant supports

What the research supports

Antioxidantmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
100 mg
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodWith a meal containing fat for fat-soluble compounds; otherwise either.
Best formMost evidence is based on the capsule or softgel form.
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Side effects & interactions

Common side effects

  • Poor absorption

Medication interactions

Prescription medications (general)minor

Always disclose Ellagic Acid use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • NAD+ precursor (NMN or NR)Complementary mitochondrial and sirtuin support.
  • Omega-3Lowers inflammation and supports membrane integrity.

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Ellagic Acid — Antioxidant ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Ellagic Acid and "Antioxidant". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Ellagic Acid — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Ellagic Acid and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Ellagic Acid — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Ellagic Acid and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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