Overview
NEM hydrolyzed eggshell for joints.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Provides collagen, glycosaminoglycans, and hyaluronic acid.
- · Provides collagen, glycosaminoglycans
- · and hyaluronic acid
Effects on the body
Organ system effects
Evidence-based benefits
Reduces joint pain
Moderate evidencePotential side effects
- · Egg allergy
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
NEM in OA
Ruff KJ, et al.
67 OA patients
Reduced pain and stiffness at 30 days.
PubMed: Eggshell Membrane — Reduces joint pain
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PubMed: Eggshell Membrane — randomized controlled trial
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