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Echinacea Angustifolia

Narrow-leaf coneflower for immune support.

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Overview

Narrow-leaf coneflower for immune support.

Natural sources
  • Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
  • Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
  • Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
Common forms
  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Mechanism of action

Higher alkylamide content than purpurea.

Pathways
  • · Higher alkylamide content than purpurea

Effects on the body

Decreases
URTI symptoms

Organ system effects

Immune System

Echinacea Angustifolia modulates innate and adaptive immune responses, including cytokine signaling and barrier function.

Evidence-based benefits

Reduces URTI symptoms

Moderate evidence

Potential side effects

Common
  • · GI upset
  • · Rash
Rare
    Serious

      Drug interactions

      Prescription medications (general)
      Always disclose Echinacea Angustifolia use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
      minor

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid if you are
      • ·Pregnant or breastfeeding (insufficient safety data)
      • ·Children under 18 (unless directed by a clinician)
      Avoid with these conditions
      • ·Autoimmune disease (theoretical immune activation)
      Avoid / monitor with these medications
      • ·Immunosuppressants

      Supplement interactions

      Pairs well with
      • Vitamin D3 + K2
        Foundational immune modulation.
      • Zinc
        Required cofactor for innate and adaptive immune function.
      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      300 mg TID
      Best form
      Most evidence is based on the standardized extract capsule form.
      Timing
      Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
      With food?
      Either with or without food.

      Where to buy

      Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Scientific evidence8Show studies
      Meta-analysisCochrane · 2014

      Echinacea for common cold

      Karsch-Volk M, et al.

      24 RCTs

      Key findings

      Modest benefit for prevention.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Echinacea Angustifolia — Reduces URTI symptoms

      Live PubMed search

      Live results for "Echinacea Angustifolia Reduces URTI symptoms" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Echinacea Angustifolia and "Reduces URTI symptoms". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Echinacea Angustifolia — randomized controlled trial

      Live PubMed search

      Live results for "Echinacea Angustifolia randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Echinacea Angustifolia and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Echinacea Angustifolia — meta-analysis

      Live PubMed search

      Live results for "Echinacea Angustifolia meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Echinacea Angustifolia and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Echinacea Angustifolia — pharmacokinetics

      Live PubMed search

      Live results for "Echinacea Angustifolia pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Echinacea Angustifolia and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Echinacea Angustifolia — safety adverse events

      Live PubMed search

      Live results for "Echinacea Angustifolia safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Echinacea Angustifolia and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Echinacea Angustifolia — dose response

      Live PubMed search

      Live results for "Echinacea Angustifolia dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Echinacea Angustifolia and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Echinacea Angustifolia — clinical evidence

      Live Scholar search

      Cross-database citation index for Echinacea Angustifolia as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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