Supplement Scholar
Peptide

CJC-1295

Prescription drug or research compound. Use only under the care of a licensed prescriber. Information here is educational and not a recommendation to obtain or use it.

CJC-1295. GHRH analog with extended half-life.

How it works. Binds albumin via DAC for prolonged GHRH activity.

What the research supports. 1 graded claims. Strongest: Sustained GH and IGF-1 elevation (moderate).

How much to take. Typical dose: 1–2 mg weekly.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Creatine monohydrate, Whey or EAAs.

Common forms. Available as Subcutaneous injection, Oral or sublingual lozenge, Nasal spray, Compounded topical.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried CJC-1295. Anecdotes are not medical advice.

CJC-1295. GHRH analog with extended half-life.

29-residue chainC165H269N47O46 · 3647.2 g/mol

What it is

GHRH analog with extended half-life.

Food sources

Synthetic peptide manufactured to pharmaceutical or research-grade puritySubcutaneous injection, sublingual, or oral preparation depending on bioavailabilityCompounded by a licensed pharmacy for clinical use

Goals

Muscle Growth

How it works

Binds albumin via DAC for prolonged GHRH activity.

Pathways

  • Binds albumin via DAC for prolonged GHRH activity

Effects

  • +Sustained GH and IGF-1 elevation supports

What the research supports

Sustained GH and IGF-1 elevationmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
1–2 mg weekly
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither with or without food.
Best formMost evidence is based on the subcutaneous injection form.

Side effects & interactions

Common side effects

  • Injection site reactions

Medication interactions

Prescription medications (general)minor

Always disclose CJC-1295 use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • Creatine monohydrateFoundational support for strength, power, and lean mass.
  • Whey or EAAsProvides amino acid substrate for muscle protein synthesis.

Common forms

  • Subcutaneous injection
  • Oral or sublingual lozenge
  • Nasal spray
  • Compounded topical

Key studies

8 studies cited in total.

PubMed: CJC-1295 — Sustained GH and IGF-1 elevation ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching CJC-1295 and "Sustained GH and IGF-1 elevation". Filter by RCT, meta-analysis, or year on the results page.

PubMed: CJC-1295 — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching CJC-1295 and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: CJC-1295 — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching CJC-1295 and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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