Overview
Trivalent chromium for glucose handling.
- Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)
- Fortified foods such as cereals, breads, plant milks, and table salt
- Mineral supplements as chelates, citrates, glycinates, or inorganic salts
- Chelated form (glycinate, bisglycinate, citrate, malate)
- Inorganic salt (oxide, sulfate, chloride)
- Liquid ionic solution
- Topical or transdermal preparation
Mechanism of action
Potentiates insulin via chromodulin.
- · Potentiates insulin via chromodulin
Effects on the body
Organ system effects
Chromium Picolinate affects hepatic insulin sensitivity, lipid handling, or glucose disposal.
Evidence-based benefits
Modest HbA1c reduction
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Chromium meta-analysis
Suksomboon N, et al.
25 RCTs
Reduced fasting glucose and HbA1c.
PubMed: Chromium Picolinate — Modest HbA1c reduction
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PubMed: Chromium Picolinate — randomized controlled trial
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PubMed: Chromium Picolinate — meta-analysis
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PubMed: Chromium Picolinate — pharmacokinetics
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PubMed: Chromium Picolinate — dose response
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Google Scholar: Chromium Picolinate — clinical evidence
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