Overview
Acute stroke neuroprotection.
- Manufactured pharmaceutical-grade compound
- Standardized botanical extract (for plant-derived nootropics)
- Stack formulations combined with cholinergic or adaptogenic ingredients
- Capsule
- Powder for stacking
- Sublingual tablet
- Liposomal liquid
Mechanism of action
Stabilizes neuronal membranes post-ischemia.
- · Stabilizes neuronal membranes post-ischemia
Effects on the body
Organ system effects
CDP-Choline (Citicoline)-Stroke acts on central nervous system targets implicated in attention, memory, and neuroprotection.
Evidence-based benefits
Improves stroke recovery
Moderate evidencePotential side effects
- · Insomnia
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
- Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified CDP-Choline (Citicoline)-Stroke — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.CDP-Choline (Citicoline)-Stroke third party tested NSF
CapsulesPre-measured CDP-Choline (Citicoline)-Stroke capsules — easiest for travel and consistent daily dosing without scoops or scales.CDP-Choline (Citicoline)-Stroke capsules
PowderBulk unflavored CDP-Choline (Citicoline)-Stroke powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.CDP-Choline (Citicoline)-Stroke powder unflavored
Best sellersMost-purchased CDP-Choline (Citicoline)-Stroke products on Amazon — a quick way to see what's reviewed widely before you commit.CDP-Choline (Citicoline)-Stroke best sellerScientific evidence8Show studiesHide studies
Citicoline in acute stroke
Davalos A, et al.
2298 stroke patients
No benefit in ICTUS trial.
PubMed: CDP-Choline (Citicoline)-Stroke — Improves stroke recovery
Live PubMed search
Live results for "CDP-Choline (Citicoline)-Stroke Improves stroke recovery" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching CDP-Choline (Citicoline)-Stroke and "Improves stroke recovery". Filter by RCT, meta-analysis, or year on the results page.
PubMed: CDP-Choline (Citicoline)-Stroke — randomized controlled trial
Live PubMed search
Live results for "CDP-Choline (Citicoline)-Stroke randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching CDP-Choline (Citicoline)-Stroke and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
PubMed: CDP-Choline (Citicoline)-Stroke — meta-analysis
Live PubMed search
Live results for "CDP-Choline (Citicoline)-Stroke meta-analysis" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching CDP-Choline (Citicoline)-Stroke and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.
PubMed: CDP-Choline (Citicoline)-Stroke — pharmacokinetics
Live PubMed search
Live results for "CDP-Choline (Citicoline)-Stroke pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching CDP-Choline (Citicoline)-Stroke and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.
PubMed: CDP-Choline (Citicoline)-Stroke — safety adverse events
Live PubMed search
Live results for "CDP-Choline (Citicoline)-Stroke safety adverse events" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching CDP-Choline (Citicoline)-Stroke and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.
PubMed: CDP-Choline (Citicoline)-Stroke — dose response
Live PubMed search
Live results for "CDP-Choline (Citicoline)-Stroke dose response" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching CDP-Choline (Citicoline)-Stroke and "dose response". Filter by RCT, meta-analysis, or year on the results page.
Google Scholar: CDP-Choline (Citicoline)-Stroke — clinical evidence
Live Scholar search
Cross-database citation index for CDP-Choline (Citicoline)-Stroke as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.