Black Cohosh
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Black Cohosh. Standardized extract for menopausal vasomotor symptoms.
How it works. Non-estrogenic; possibly modulates serotonin and dopamine receptors.
What the research supports. 1 graded claims. Strongest: Reduces menopausal hot flashes (moderate).
How much to take. Typical dose: 20–40 mg Remifemin × 2/d.
Side effects and interactions. 2 medication interactions listed. Serious: Hepatotoxicity (rare case reports).
Stacking. Pairs well with A high-quality multivitamin, Omega-3 (EPA/DHA). Avoid combining with Liver disease.
Common forms. Available as Remifemin standardized.
Key studies. 8 studies cited. The strongest are listed with links to PubMed.
Community. Experiences from people who have tried Black Cohosh. Anecdotes are not medical advice.
Black Cohosh. Standardized extract for menopausal vasomotor symptoms.
What it is
Standardized extract for menopausal vasomotor symptoms.
Also called
Food sources
Goals
How it works
Non-estrogenic; possibly modulates serotonin and dopamine receptors.
Pathways
- Serotonergic
Effects
- ↓Hot flashes decreases
What the research supports
Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.
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Side effects & interactions
Common side effects
- GI upset
Serious
- Hepatotoxicity (rare case reports)
Medication interactions
Caution.
Uncertain interaction.
Check any supplement–medication combination with your pharmacist before starting.
Combines with
Pairs well
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
Avoid combining
- Liver diseaseHepatotoxicity reports.
Common forms
- Remifemin standardized
Key studies
8 studies cited in total.
Insufficient evidence to support routine use.
Opens current human and preclinical literature matching Black Cohosh and "Reduces menopausal hot flashes". Filter by RCT, meta-analysis, or year on the results page.
Opens current human and preclinical literature matching Black Cohosh and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
Discussion
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