Overview
Psychobiotic for stress and mood.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Modulates HPA axis via vagus nerve.
- · Modulates HPA axis via vagus nerve
Effects on the body
Organ system effects
Bifidobacterium Longum 1714 modulates monoaminergic and GABAergic tone relevant to mood and anxiety regulation.
Bifidobacterium Longum 1714 influences gut motility, mucosal integrity, or microbial balance in the GI tract.
Evidence-based benefits
Reduces stress response
Moderate evidencePotential side effects
- · Mild GI
Drug interactions
Supplement interactions
- Multi-strain probioticSupports microbiome diversity and barrier integrity.
- L-glutamineSubstrate for enterocyte energy and tight-junction maintenance.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
B. longum 1714 stress
Allen AP, et al.
22 healthy men
Reduced cortisol and improved memory.
PubMed: Bifidobacterium Longum 1714 — Reduces stress response
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