Overview
Scutellaria baicalensis flavonoid.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
GABA-A modulator; anti-inflammatory.
- · GABA-A modulator
- · anti-inflammatory
Effects on the body
Organ system effects
Baicalin modulates monoaminergic and GABAergic tone relevant to mood and anxiety regulation.
Baicalin modulates innate and adaptive immune responses, including cytokine signaling and barrier function.
Evidence-based benefits
Reduces anxiety (preclinical)
Moderate evidencePotential side effects
- · Well tolerated
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Autoimmune disease (theoretical immune activation)
- ·Immunosuppressants
Supplement interactions
- Vitamin D3 + K2Foundational immune modulation.
- ZincRequired cofactor for innate and adaptive immune function.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified Baicalin — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Baicalin third party tested NSF
CapsulesPre-measured Baicalin capsules — easiest for travel and consistent daily dosing without scoops or scales.Baicalin capsules
PowderBulk unflavored Baicalin powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Baicalin powder unflavored
Best sellersMost-purchased Baicalin products on Amazon — a quick way to see what's reviewed widely before you commit.Baicalin best sellerScientific evidence8Show studiesHide studies
Baicalin anxiolytic
Liao JF, et al.
Elevated plus-maze
Anxiolytic effects via GABA.
PubMed: Baicalin — Reduces anxiety
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PubMed: Baicalin — randomized controlled trial
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PubMed: Baicalin — meta-analysis
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PubMed: Baicalin — pharmacokinetics
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PubMed: Baicalin — safety adverse events
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PubMed: Baicalin — dose response
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Google Scholar: Baicalin — clinical evidence
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Cross-database citation index for Baicalin as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.