Overview
Rare sugar with minimal calories.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Not metabolized; inhibits intestinal sucrase.
- · Not metabolized
- · inhibits intestinal sucrase
Effects on the body
Organ system effects
Allulose affects hepatic insulin sensitivity, lipid handling, or glucose disposal.
Evidence-based benefits
Lowers postprandial glucose
Moderate evidencePotential side effects
- · GI upset at high dose
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Allulose and glucose
Hayashi N, et al.
26 adults
Reduced postprandial glucose response.
PubMed: Allulose — Lowers postprandial glucose
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PubMed: Allulose — randomized controlled trial
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PubMed: Allulose — meta-analysis
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PubMed: Allulose — pharmacokinetics
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PubMed: Allulose — safety adverse events
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PubMed: Allulose — dose response
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Google Scholar: Allulose — clinical evidence
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Cross-database citation index for Allulose as it relates to "clinical evidence".
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