Aged Garlic Extract (Kyolic)
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Aged Garlic Extract (Kyolic). Odorless aged garlic with S-allyl-cysteine for vascular health.
How it works. S-allyl-cysteine inhibits ACE and reduces oxidative stress in endothelium.
What the research supports. 2 graded claims. Strongest: Lowers blood pressure in uncontrolled hypertension (strong).
How much to take. Typical dose: 240–960 mg AGE.
Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.
Stacking. Pairs well with Omega-3, CoQ10, Vitamin D3 + K2.
Common forms. Available as Standardized extract capsule, Liquid tincture (alcohol or glycerin), Powdered whole herb, Traditional decoction or tea.
Key studies. 9 studies cited. The strongest are listed with links to PubMed.
Community. Experiences from people who have tried Aged Garlic Extract (Kyolic). Anecdotes are not medical advice.
Aged Garlic Extract (Kyolic). Odorless aged garlic with S-allyl-cysteine for vascular health.
What it is
Odorless aged garlic with S-allyl-cysteine for vascular health.
Food sources
Goals
How it works
S-allyl-cysteine inhibits ACE and reduces oxidative stress in endothelium.
Pathways
- S-allyl-cysteine inhibits ACE
- reduces oxidative stress in endothelium
Effects
- ↓blood pressure in uncontrolled hypertension decreases
- +Slows coronary calcium progression supports
What the research supports
Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.
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Side effects & interactions
Common side effects
- Mild GI upset
Medication interactions
Mild antiplatelet effect.
Check any supplement–medication combination with your pharmacist before starting.
Combines with
Pairs well
- Omega-3Anti-inflammatory cardiovascular synergy.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
- Vitamin D3 + K2Foundational immune modulation.
Common forms
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Key studies
9 studies cited in total.
Opens current human and preclinical literature matching Aged Garlic Extract (Kyolic) and "Lowers blood pressure in uncontrolled hypertension". Filter by RCT, meta-analysis, or year on the results page.
Opens current human and preclinical literature matching Aged Garlic Extract (Kyolic) and "Slows coronary calcium progression". Filter by RCT, meta-analysis, or year on the results page.
Opens current human and preclinical literature matching Aged Garlic Extract (Kyolic) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
Discussion
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