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Mushroom

Agarikon (Fomitopsis officinalis)

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Agarikon (Fomitopsis officinalis). Antiviral polypore mushroom.

How it works. Triterpenes with broad antiviral activity.

What the research supports. 1 graded claims. Strongest: Antiviral (preclinical) (moderate).

How much to take. Typical dose: 500 mg.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Vitamin D3 + K2, Zinc.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Agarikon (Fomitopsis officinalis). Anecdotes are not medical advice.

Agarikon (Fomitopsis officinalis). Antiviral polypore mushroom.

Key compound: agaric acidC22H40O7 · 416.5 g/mol

What it is

Antiviral polypore mushroom.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

Immune Function

How it works

Triterpenes with broad antiviral activity.

Pathways

  • Triterpenes with broad antiviral activity

Effects

  • +Antiviral (preclinical) supports

What the research supports

Antiviral (preclinical)moderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
500 mg
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither with or without food.
Best formMost evidence is based on the capsule or softgel form.
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Side effects & interactions

Common side effects

  • Bitter taste

Medication interactions

Prescription medications (general)minor

Always disclose Agarikon (Fomitopsis officinalis) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • Vitamin D3 + K2Foundational immune modulation.
  • ZincRequired cofactor for innate and adaptive immune function.

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Agarikon (Fomitopsis officinalis) — Antiviral ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Agarikon (Fomitopsis officinalis) and "Antiviral". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Agarikon (Fomitopsis officinalis) — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Agarikon (Fomitopsis officinalis) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Agarikon (Fomitopsis officinalis) — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Agarikon (Fomitopsis officinalis) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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