Overview
β-carboline alkaloid that upregulates dopamine neurons in animal models.
- Manufactured pharmaceutical-grade compound
- Standardized botanical extract (for plant-derived nootropics)
- Stack formulations combined with cholinergic or adaptogenic ingredients
- Capsule
- Powder for stacking
- Sublingual tablet
- Liposomal liquid
Mechanism of action
MAO-A inhibition plus dopaminergic neurogenesis in substantia nigra (rodent data).
- · MAO-A inhibition plus dopaminergic neurogenesis in substantia nigra (rodent data)
Effects on the body
Organ system effects
9-Me-BC acts on central nervous system targets implicated in attention, memory, and neuroprotection.
Evidence-based benefits
Increases dopamine neuron count in rats
Limited evidencePotential side effects
- · Headache
- · Limited human safety data
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
- Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.
- NAD+ precursor (NMN or NR)Complementary mitochondrial and sirtuin support.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified 9-Me-BC — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.9-Me-BC third party tested NSF
CapsulesPre-measured 9-Me-BC capsules — easiest for travel and consistent daily dosing without scoops or scales.9-Me-BC capsules
PowderBulk unflavored 9-Me-BC powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.9-Me-BC powder unflavored
Best sellersMost-purchased 9-Me-BC products on Amazon — a quick way to see what's reviewed widely before you commit.9-Me-BC best sellerScientific evidence8Show studiesHide studies
9-Me-BC restores dopamine in MPTP-lesioned mice
Polanski W, et al.
Mouse Parkinson's model treated with 9-Me-BC.
Restored striatal dopamine and TH-positive neuron count.
PubMed: 9-Me-BC — Increases dopamine neuron count in rats
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PubMed: 9-Me-BC — dose response
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Google Scholar: 9-Me-BC — clinical evidence
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