Supplement Scholar
Healing & Repair

Pentadeca Arginate (PDA)

Research compound. This is not a dietary supplement. Unless it is identified as an approved prescription drug, it is not approved by the FDA for human use. This page summarizes published research for education only; we do not sell it or link to sellers.

Pentadeca Arginate (PDA). A BPC-157-derived peptide marketed as a more stable alternative. It has almost no published research of its own.

How it works. Presumed to share BPC-157's proposed actions: new blood-vessel growth via VEGFR2, nitric-oxide modulation, and faster tendon and gut healing in animals.

What the research supports. 1 graded claims. Strongest: Tissue-repair claims extrapolated from BPC-157 animal studies (preclinical).

Side effects and interactions. 0 medication interactions listed. Serious: Unregulated products with unknown purity.

Stacking. Avoid combining with Active cancer.

Common forms. Available as Subcutaneous injection (compounded), Oral (compounded).

Community. Experiences from people who have tried Pentadeca Arginate (PDA). Anecdotes are not medical advice.

Pentadeca Arginate (PDA). A BPC-157-derived peptide marketed as a more stable alternative. It has almost no published research of its own.

No single structure

What it is

Sold since 2024 as a stabilized relative of BPC-157, mainly after compounding pharmacies lost access to BPC-157. Its claims rest on BPC-157's animal research, not studies of PDA itself.

Also called

PDA

How it works

Presumed to share BPC-157's proposed actions: new blood-vessel growth via VEGFR2, nitric-oxide modulation, and faster tendon and gut healing in animals.

Pathways

  • VEGFR2 signaling (presumed)
  • Nitric oxide system (presumed)

Effects

  • +Tissue repair (extrapolated from BPC-157) supports

What the research supports

Tissue-repair claims extrapolated from BPC-157 animal studiespreclinical

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Side effects & interactions

Common side effects

  • Injection-site irritation

Serious

  • Unregulated products with unknown purity

No notable medication interactions listed.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Avoid combining

  • Active cancerNew blood-vessel growth is undesirable when tumors are present.

Common forms

  • Subcutaneous injection (compounded)
  • Oral (compounded)

Discussion

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